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Oral + Respiratory Defense are chewable, strawberry-flavored probiotic tablets that activate in the oral cavity for support of ear, nose, and throat health and to naturally promote fresh breath. As you chew, each tablet releases the DSM 13084 strain of Streptococcus salivarius, a beneficial bacterium that normally occurs in a healthy oral cavity. S salivarius adheres to cells in the cavity and positively affects the bacterial population and natural immune defenses therein. Once established, S salivarius DSM 13084 also naturally counteracts the production of volatile sulfur compounds that can cause bad breath.*
Suggested Use: As a maintenance dose, after your bedtime oral hygiene routine chew one tablet slowly and completely before swallowing. During periods of increased need, chew up to five tablets per day in divided dose for 90 days, or as directed by your healthcare professional.
Children and pregnant or lactating women should consult their healthcare practitioner prior to use. Do not use if foil is punctured.
Package Contains: 30 capsules
Ingredients: Streptococcus salivarus DSM 13084 (1 Billion CFU)
Does Not Contain: Wheat, gluten, soy, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, or preservatives.
The oral cavity is home to a plethora of naturally occurring bacteria. Some of these microorganisms are an important aspect of maintaining good health and serve as a first line of defense. Streptococcus salivarius is one of the most numerous of these “good” bacteria found in the mouths of healthy individuals. It is becoming more evident that a healthy balance of bacteria in the mouth and promoting the presence of specific strains of certain bacteria in it may be important for throat, nasopharyngeal, and middle ear health.*1-4
Strain DSM 13084
S salivarius DSM 13084 (also known as ATCC BAA-1 024), found in Oral + Respiratory Defense, was discovered and isolated by renowned microbiologist Professor John Tagg at the University of Otago in New Zealand. Spurred by his own experiences as a youth, he was determined to find a natural and proactive way to help support throat health, especially in children. Dr. Tagg followed New Zealand school children for many years, analyzing their saliva samples and looking for differences. A breakthrough came when Dr. Tagg and his team isolated the unique DSM 13084 strain of S salivarius from a healthy child who, over a six-year period, exhibited remarkable throat health. Work was then begun to develop this strain for use as an advanced probiotic in the wellness market. DSM 13084 is an extremely safe yet powerful strain that has been deposited in culture collections.*5-7
DSM 13084 has been shown to adhere to cells of the oral cavity and populate therein.4,8-10 Not only does this strain exert its benefits through the typical colonization or “power in numbers” method, but it also produces several bioactive peptides, including salivaricin A and salivaricin B, that support oral health.*4,8,11,12
Ear, Nose/Nasopharynx, and Throat Health
Oral + Respiratory Defense represent a new “bioprotic” approach; that is, using probiotics to enhance health in non-intestinal sites for specific applications.8 DSM 13084 promotes healthy levels of beneficial oral microorganisms, and thereby supports upper respiratory health.9 Studies suggest that children with naturally occurring S salivarius DSM 13084-like strains are better able to maintain healthy mouth and throat microbial populations. Preliminary studies performed in children and adults have shown that supplementation with DSM 13084 has a statistically significant impact on throat, tonsil, and middle ear health.4,8 In addition, preliminary in vitro and animal data from a 2012 study suggest that DSM 13084 positively affects the presence of Candida albicans in the oral mucosa and may inhibit its attachment to denture acrylic resins.*13
The predominant microbiota on the tongue of subjects with and without bad breath differs.14 When certain bacteria break down proteins on the tongue, volatile sulfur compounds (VSC) that cause bad breath are released. In a placebo-controlled trial, Burton et al showed that administration of the DSM 13084 strain in 13 subjects resulted in a substantial decrease in VSC levels compared to controls.15 The introduction of DSM 13084 helps balance the microflora of the mouth because it competes with the sulfur-producing bacteria for space while leaving room for more good bacteria to flourish.15-17 This method of supporting a microbial population that limits the activities of sulfur-producing bacteria gets to the source of bad breath.15,16 Addressing bad breath at its source can provide longer-lasting results than methods that simply mask odors.*
*For Best Results: Oral + Respiratory Defense tablets should be chewed slowly and thoroughly, ideally after the patient’s oral hygiene routines (e.g., brushing, flossing, rinsing). Waiting until the tablet is completely dissolved before swallowing is optimal. The tablets do not contain cariogenic sugars or other ingredients that could negatively affect dental health.
10. Streptococcus salivarius K12 colonisation – dose response. BLIS Technologies Ltd. June 9, 2009. Data on file.