Guggul Lean Capsules
LifeSpa Whole Herbs™
Metabolism & Thyroid Support*
472mg | 90 caps
Guggul Lean is a proprietary herbal formula combining guggul with arjuna, black pepper, amalaki, turmeric, and shilajit to boost its absorption and effectiveness. It supports healthy cholesterol particles, detoxification, joint health, thyroid health, and healthy weight management.*
Guggul (Commiphora mukul) is a tree resin that is perhaps the most famous Ayurvedic substance known for supporting cholesterol levels already within a normal range and a healthy stress response. This resin is rich in extremely active guggulsterones. Guggul was traditionally used in Ayurveda to support the utilization of fat as the body’s fuel source, helping to stabilize weight, energy levels, mood and mental clarity, among many others functions in the body. Guggul is balancing to kapha and its potent detoxification properties are also beneficial for individuals who are in the process of purifying from a toxic lifestyle.*
Suggested Use: Take 1 capsule 2 times per day after meals, or as directed by your healthcare professional.
Bottle Contains: 90 vegetarian capsules, 472mg each
Ingredients: Organic Terminalia arjuna (Arjuna Bark), Organic Curcuma longa (Turmeric Root), Organic Phyllanthus emblica (Amalaki Fruit) Commiphora mukul (Guggul Gum Extract), Asphaltum punjabianum (Shilajit Extract), Organic Piper nigrum (Black Pepper Fruit)
Does not contain: Yeast, gluten, corn, soy, milk, fish, animal products, binders, fillers, preservatives or artificial coloring.
Kosher Certified: No animal derivatives
Cholesterol has been under much media scrutiny of late as the medical establishment continues to argue over the still unresolved issue of whether or not saturated fat – which is high in cholesterol – is evil or not. Today, the evidence is mounting against this theory, suggesting that high cholesterol has much less to do with the increased risk of heart disease than originally thought.
One such study published in the prestigious medical journal, The Lancet, compared folks on a relatively high cholesterol Mediterranean diet with those on a medically supervised low cholesterol diet. There was a 70% reduction in risk of overall death and a 76% reduction in risk of cardiovascular-related death in the Mediterranean diet group compared to the low cholesterol and low saturated fat diet. Interestingly, the group on the low cholesterol, low saturated fat diet showed no change in their overall cholesterol or LDL levels. (1)
To explain these findings, it might help to understand cholesterol’s role in health. Cholesterol is essential for life and is primarily manufactured in the liver, but other cells in the body also form cholesterol. Cholesterol is a fat that helps your skin repel water. It is the primary component of all of your hormones, it is a major building block molecule for many structures of the body, and helps the skin on the inside and outside of the body ward off toxic chemicals as well as hold precious water and moisture in. (2)
The problems arise when these HDL and LDL particles are oxidized or damaged. Some of this oxidative damage can come from toxins in the environment like cigarette smoke, heavy metal exposure, and stress. Living a stress-free life, meditating or prayer, eating whole non-processed foods, avoiding alcohol in excess, breathing clean air and drinking clean water will decrease the oxidation of the LDL and HDL cholesterol particles. (3,4)
Focusing on removing the cholesterol from the blood may, in fact, decrease cardiovascular risk for only a select few. Ayurveda focuses on how the more dangerous particles become elevated or oxidized in the first place and how to prevent it. When looking to support healthy lipid levels, seek out a comprehensive approach that includes diet, lifestyle, and the restoration of optimal digestion and healthy detoxification.
In Ayurveda, Guggul is considered to be the most powerful remedy for the buildup of ama which results in an imbalanced of cholesterol and blood lipid metabolism. This is now being supported by studies which guggul’s positive effect on healthy cholesterol levels. (5-7)
In one study, individuals taking 50mg of a guggul extract in addition to a fruit- and vegetable-enriched prudent diet saw an overall decrease in serum triglycerides of 12% and a reduction in lipid peroxidation, an indicator of oxidative stress, by 33.3%, compared to no change in the placebo group. (5)
In another study, when supplemented with 500mg of a guggul extract for 12 weeks, an average reduction in serum triglycerides of 16.8% was observed. In the same study, an improvement in HDL levels was found in 60% of the individuals taking the extract. (7)
These results suggest that guggulsterones may support healthy oxidation of LDL cholesterol and impede the formation of hydroxyl radicals, which is a potent type of free radical that attacks cell membranes. (8)
Note: While there are many studies that show significant support for healthy cholesterol with Guggul, it should be mentioned that some studies do not show these same benefits. Any cholesterol-lowering regime must include dietary changes, exercise, and, of course, improving one’s digestive function. The lack of such a comprehensive approach to healthy weight and healthy cholesterol may explain the varied results.
In one study, guggul was shown to boost the uptake of iodine into the thyroid gland. This was likely due to enhanced activation of thyroid peroxidase and protease, as well as oxygen consumption they found associated with guggul supplementation. (9)
In another study on guggul supplementation, results suggested that certain constituent factors have the ability to counteract thyroid dampening agents in otherwise healthy subjects. (10)
Other research found that after 30 days of supplementation, certain constituents in guggul were found to boost the activity of superoxide dismutase (SOD), catalase (CAT) and lipid peroxides (LPO) — enzymes which support healthy thyroid function. This increased antioxidant activity is thought to be responsible for the increase in T3 and T4 thyroid hormone levels also noted in this study. (11)
The Link between Healthy Weight and Thyroid
Ayurvedically, weight gain has often been linked to imbalanced thyroid function. Guggul has been traditionally used to support the utilization of fat as the body’s fuel source, helping to stabilize weight, energy levels, mood and mental clarity, among many others functions in the body.
Metabolic rates are affected by the overall health of the thyroid, which seems to be a persistent and growing concern in America. The American Thyroid Association estimates that 20 million Americans have some form of thyroid condition and up to 60% of them are unaware of their condition. (12)
Numerous studies on guggul show impressive support for normal thyroid function and healthy weight loss. In one study, overweight individuals on guggul supplementation, alongside diet and regular exercise, experienced a significant decrease in body weight and fat mass, as well as an improved mood state, according to self-report. (13)
There are active plant steroids found in the resin of the guggul plant called guggulsterones. These guggulsterones have been shown to support optimal thyroid health– meaning they help stimulate the body’s natural ability to regulate metabolism. (10) Research suggests that guggulsterones can modify the rate and amount of bile salt transported out of the liver. (14-16)
Numerous studies have shown that guggul supports weight management and fat burning. In one study, it supported healthy cholesterol (5) and restored healthy body weight in animals fed a high-fat diet in another. (6)
Fat-Burning Delivers More than Weight Loss
It is understood that the harmful chemicals in the environment are fat-soluble, and the ability for the body to rid itself of them requires good fat metabolism, which we see supported by guggul supplementation.
Fat-soluble chemicals are particularly toxic to the heart and the arteries, as well as the thyroid – which may be the most chemical-sensitive organ of all. In situations where the heart and arteries were exposed to oxidizing chemicals, the guggul supplemented group saw a significant increase in the natural production of the following antioxidants: glutathione, superoxide dismutase, catalase and lipid peroxidase in the arteries of the heart. (17)
In another study, guggul supplementation was linked to decreased lipid peroxidation – a process involved in the oxidation of the liver. The guggul supplemented group also saw an increased concentration of thyroid hormone (T3) and enhanced T3/T4 ratios. (18)
Recently, guggul has been linked to healthy joint function and higher levels of collagen and protein in the cartilage of aging knees in animal models. In the study, the group that had higher blood levels of guggulsterones also had thicker cartilage and higher bone density compared to those who received a sodium chloride solution. (19)
Ayurvedic Herbal Makeup
2. Guyton and Hall. textbook of Medical Physiology. 12th edition. Saunders Press 2011. p Ch 68. p826
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