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Chelation Support

Chelation Support
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Description
Chelation Support is designed to help the body rid itself of damaging oxidative elements. It features specialized ingredients, such as EDTA, Himalayan shilajit extract (50% fulvic acid), chlorella, cilantro, and antioxidant-stimulating nutrients. These ingredients perform in concert to support your health when your body is challenged by environmental toxins, such as heavy metals.*

Suggested Use: Take two to four capsules daily, or as directed by your healthcare practitioner.

Consult your healthcare practitioner prior to use. Individuals taking blood thinners, insulin, or other medication should discuss potential interactions with their healthcare practitioner. Do not take if you are pregnant or lactating. Do not use if tamper seal is damaged.

Bottle Contains: 120 capsules
Ingredients: Himalayan Shilajit Extract, Calcium Disodium EDTA, Chlorella, Cilantro Aqueous Extract, N-Acetyl-L-Cysteine, Alpha-Lipoic Acid, Allicin
Other Ingredients: HPMC (capsule), dicalcium phosphate, stearic acid, magnesium stearate, silica, and medium-chain triglycerides.
Does Not Contain: Wheat, gluten, yeast, soy, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, artificial colors, artificial sweeteners, or preservatives.

The Science
Himalayan Shilajit Extract (Asphaltum punjabinum) is a purified form of shilajit also known as salajit, shilajatu, mimie, or mummiyo. This naturally occurring phytocomplex is found in high mountain rocks, especially those of the Himalayas and Hindu Kush ranges of the Indian subcontinent. It is formed from decomposed plant material that has been preserved in the dark pressure of rocky crevasses. As the sun warms the rocks and the snow melts, the shilajit seeps out and is scraped from the stone by hand. LifeSpa’s shilajit is meticulously harvested at high altitudes to ensure the purest product possible. It is then low-temperature dried and tested to be free of pollutants. Shilajit is composed mainly of humic substances, including fulvic acid, plus some oligoelements (minute amounts of trace elements). It has a rich history of use in the Indian Ayurvedic and Siddha systems of medicine, and it is known as a rasayana because of its rejuvenating qualities.*1

Modern research suggests that shilajit has powerful antioxidant activity.1-3 As an example, in an animal model, processed shilajit increased superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) activities in a dose-dependent manner.3 Furthermore, humic substances, as found in shilajit, have been shown to affect the distribution, metabolism, and absorption of heavy metals, such as cadmium and lead.4-7 One human study showed that the daily consumption of humic acid with bound complex micro-elements for six weeks decreased uptake and increased urinary excretion of cadmium in alkaline battery production workers.*8

EDTA (ethylenediaminetetraacetic acid) is a synthetic amino acid compound and perhaps the most well-known and often-used intravenous chelating agent. Oral EDTA is poorly absorbed, but it is thought to support detoxification of metals largely in the gastrointestinal tract.9,10 More studies are needed to validate oral administration. It is believed that there is a benefit in combining EDTA with other chelators because EDTA acts slowly and could potentially lead to redeposition of metals.11 Due to EDTA’s metal-binding ability, it is important to replace beneficial minerals, such as zinc, copper, iron, cobalt, and manganese.*

Cilantro (Coriandrum sativum), also known as Chinese parsley or coriander, suppresses the deposition of lead by chelating the metal.12 Furthermore, in an experimental animal study, lead-induced histological changes in the testis of albino mice were prevented to some extent by concomitant daily administration of C sativum extracts, perhaps due to a reduction in associated oxidative stress.*13

Allicin is the main biologically active component of garlic clove extracts and has promising effects on toxic metal accumulation in experimental research.14 In animal and in vitro models, garlic was able to reduce cellular exposure to, or accumulation of, lead, cadmium, and mercury.15-20 Furthermore, various extracts and forms of garlic have demonstrated garlic’s ability to positively affect detoxification pathways.*20

Chlorella is a naturally occurring micro-algae and an excellent source of chlorophyll—a detoxifying substance that is also thought to bind toxic metals. The positive effect of chlorella supplementation on toxic metals, including methylmercury, cadmium, and lead, is supported by animal research.21,22 For example, testing its metal chelating ability, researchers observed a dramatic 66.03% reduction in blood lead levels in mice receiving chlorella extract (50 mg/kg/day) concurrent with lead exposure compared to lead-exposed, non-treated mice.*21

N-Acetyl-L-Cysteine (NAC) and Alpha-Lipoic Acid (ALA) are well-known for their antioxidant activity. Exposure to heavy metals increases free radical production and oxidative stress.23 Research suggests that there is a beneficial role for free radical scavengers in reducing the oxidative stress that is common with toxic metal exposure.24 NAC has the ability to interact with reactive oxygen species (ROS) andstimulate the body to produce glutathione. This can enhance cell survival after exposure to heavy metals or toxins.25 In addition, ALA may directly chelate or reduce the oxidative capacity of metals, such as copper, arsenic, cadmium, and mercury.*26-29

References
1. http://www.ncbi.nlm.nih.gov/pubmed/ 22482077
2. Mittal P, Kaushik D, Gupta V. Therapeutic potentials of “shilajit rasayana”: a review. Int J Pharm Clin Res. 2009;1(2):47-49. http://www.rudramani.com/research/shilajit-as-a-medicine-forgeneral-physical-strengthening-anti-aging-and-much-more.pdf. Accessed August 1, 2014.
3. Bhattacharya SK, Sen AP, Ghosal S. Effects of shilajit on biogenic free radicals. Phyto Res. 1995 Feb;9(1):56-59. doi:10.1002/ptr.2650090113.
4. http://www.ncbi.nlm.nih.gov/pubmed/8750902
5. http://www.ncbi.nlm.nih.gov/pubmed/10401728
6. http://www.ncbi.nlm.nih.gov/pubmed/18958421
7. http://www.ncbi.nlm.nih.gov/pubmed/22557121
8. Hudák A, Náray M, Nagy I, et al. Effect of the consumption of humic acid with bound complex micro elements in cases of occupational cadmium exposure. National Institute of Occupational Health, Budapest, Hungary. http://www.omfi.hu/cejoem/Volume3/Vol3No3/ce973-2.HTM. Accessed July 31, 2014.
9. http://www.ncbi.nlm.nih.gov/pubmed/13163555
10. http://www.ncbi.nlm.nih.gov/pubmed/13312679
11. http://www.ncbi.nlm.nih.gov/pubmed/9202621
12. http://www.ncbi.nlm.nih.gov/pubmed/11535365
13. http://www.ncbi.nlm.nih.gov/pubmed/19902160
14. http://www.ncbi.nlm.nih.gov/pubmed/19764011
15. http://www.ncbi.nlm.nih.gov/pubmed/11448543
16. http://www.ncbi.nlm.nih.gov/pubmed/20711682
17. http://www.ncbi.nlm.nih.gov/pubmed/18719860
18. http://www.ncbi.nlm.nih.gov/pubmed/11315815
19. http://www.ncbi.nlm.nih.gov/pubmed/10565261
20. http://www.ncbi.nlm.nih.gov/pubmed/20213447
21. http://www.ncbi.nlm.nih.gov/pubmed/12781705
22. http://www.ncbi.nlm.nih.gov/pubmed/22008543
23. http://www.ncbi.nlm.nih.gov/pubmed/21845340
24. http://www.ncbi.nlm.nih.gov/pubmed/12732454
25. http://www.ncbi.nlm.nih.gov/pubmed/15527868
26. http://www.ncbi.nlm.nih.gov/pubmed/12821289
27. http://www.ncbi.nlm.nih.gov/pubmed/15603538
28. http://www.ncbi.nlm.nih.gov/pubmed/10703716
29. http://www.ncbi.nlm.nih.gov/pubmed/9020508

LifeSpa Product Line: Guaranteed To Be Pure
All of LifeSpa’s herbal formulas and supplements meet or exceed third party NSF GMP quality standards. LifeSpa’s whole leaf herbal formulas and oils contain 98% organic ingredients. All of LifeSpa’s herbal formulas are manufactured in an FDA registered facility, and are independently tested for lead and contaminants.

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* These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.

Disclaimer: The entire contents of this website are based upon the opinions of John Douillard. They are not intended to replace a one-on-one relationship with a qualified health care professional, and they are not intended as medical advice. They are intended as a sharing of knowledge and information from the research and experience of John Douillard and his community. John Douillard encourages you to make your own health care decisions based upon your research and in partnership with a qualified health care professional.